Itchy blisters on the hands may be caused by fungal infections, which can be treated with topical antifungal medications, or by sweat blisters, which can be treated with topical glucocorticoids. 1. Fungal infection: If there is a fungal infection on the hands, there will be blisters, itching, moulting and other symptoms, you can use antifungal creams, including miconazole cream, ketoconazole cream, etc. for treatment. 2. Sweat herpes: sweat herpes is a special type of hand eczema, there will be blisters on both sides of the fingers, itching, often aggravated in the summer, you can use glucocorticosteroids such as tretinoin ointment, etc., itching is serious oral antihistamine such as cetirizine. If there are blisters on the hands and itchy phenomenon, you should go to the hospital in time to check, the use of the above drugs should follow the doctor’s instructions.