There are more methods to remove wrinkles, the common ones include thread sculpture, facelift, hyaluronic acid filling, autologous fat filling, botulinum toxin injection, radiofrequency surgery, cosmetic wrinkle removal, etc. The details are as follows. 1, thread sculpture to remove wrinkles: the use of absorbable sutures not only for the skin has the role of pulling wrinkles, and can promote the subcutaneous fiber tissue remodeling, to achieve the real purpose of wrinkle removal; 2, facelift: more traditional and more expensive, need to remove part of the skin and then re-suture, traumatic, currently less used; 3, hyaluronic acid, autologous fat filling: especially for the sunken and loose skin more effective, can make Subcutaneous tissue is more plump, thus removing wrinkles, especially effective for static facial wrinkles; and autologous fat filling is similar to it, with permanent and relatively safe effects, effective for any wrinkles; 4, Botox injection: its treatment by inhibiting muscle contraction, effective for facial wrinkles that appear only when the muscles contract, such as crow’s feet and head lines; 5, cosmetic application: vitamin E, containing vitamin A acid can be used cosmetics topical application of facial skin, which helps to promote skin metabolism, antioxidant and anti-aging.