Calluses on the feet walking especially painful should be timely removal of triggering factors, and can be appropriate use of drugs such as salicylic acid. Callus is the common name for callus, mostly caused by excessive friction, should be timely replacement of inappropriate shoes, choose the right soft shoes and socks, etc., can reduce the formation of callus. In addition, hot water can be used to soak, so that the callus softened, and the use of pumice stone and other friction, easy to remove. You can also use exfoliators such as salicylic acid ointment and retinoic acid ointment to help soften the callus. Emollients such as vitamin E cream can be applied on a regular basis. If the callus symptoms are more serious, go to the hospital in time, the use of the above drugs should follow the doctor’s advice.