Duodenal bulbitis is mainly caused by severe edema at the duodenal bulb, resulting in severe vomiting, which needs to be relieved by general treatment combined with medication. 1. General treatment: regular massage of the abdomen to promote peristalsis in the duodenal bulb, to ensure rapid digestion and absorption of intestinal contents, to reduce the accumulation of food, and to reduce the symptoms of severe vomiting. If obstruction occurs, fasting is needed. 2. Medication: antibiotic drugs can be taken to relieve the edema of the duodenal bulb, thus relieving abdominal pain, vomiting and other discomforts, such as metronidazole, levofloxacin, etc.; also through the use of gastric stimulants to promote gastrointestinal peristalsis and reduce gastric retention of gastric contents, such as mosapride, doxepin, etc.. It is recommended to use medication under the guidance of a physician, not blindly use medication on your own. When discomfort occurs, it is recommended to seek immediate medical attention and early treatment under the guidance of a professional physician.