The lack of centering of the black eye can be caused by strabismus, congenital glaucoma or refractive errors, etc. Patients need to be treated with glasses, eye shields, orthokeratology, medication and surgery. 1. Strabismus: The lack of centering of the black eyeball may be caused by strabismus, which needs to be treated with glasses, eye shields, orthokeratology training, and sometimes with injections of botulinum toxin type A and other medications. 2. Congenital glaucoma: Congenital glaucoma can also be caused by increased intraocular pressure, resulting in dilation of the eyeball, making the eyeball look bigger, thus causing bilateral asymmetry, resulting in the situation that the black eyeball is not centered, which needs to be treated through the use of medications such as carteolol hydrochloride eye drops and surgery. 3. Refractive error: patients with myopia, astigmatism and other refractive errors, which are not corrected in time and affect the vision, may also cause the performance of the black eye not centered, and need to consult a doctor for examination in time, and corrected by wearing lenses and other ways. It is recommended that once a patient finds that his or her black eye is not centered, he or she should consult a doctor in time to complete the relevant examinations and standardize the treatment. In addition, drugs may cause certain side effects, should be used under the guidance of a doctor, do not blindly use drugs.