Pancreatic cancer is difficult to treat and is among the most malignant malignant tumors of the digestive system that are very difficult to treat. Usually before the end of life, it may show signs such as gradually increasing abdominal distension and jaundice. Jaundice may appear as obstructive jaundice, and the effect of general drainage or stenting will not improve significantly or will easily recur; there is also severe abdominal pain, and the pain cannot be stopped with general doses of pain medication, and morphine injection or oral medication added to a very large amount is needed to control the painful symptoms of pancreatic cancer. In addition, there may be other multiple metastases, bone metastases will have bone pain and pathological fracture, which are also signs of terminal illness; or lung metastases, which may have heavy cough, coughing sputum and hemoptysis; pancreatic cancer may also have brain metastases. If there are multiple metastases, it indicates that the disease is late and there is no way to control it, and it is a sign of terminal illness, which requires better care, better companionship and pain relief treatment.