First, the degree of tissue-matching suitability is high. Differences in human histocompatibility antigens are the immunological basis for rejection, and the degree of histocompatibility obviously affects the long-term survival of the transplanted kidney. Due to the laws of genetics, there are very few unrelated HLA identical individuals in the population, and many more among relatives. For example, there can be one haplogroup identical between parents and children; between siblings, the chance of one haplogroup identical is 50%, and two haplogroups identical or completely different are 25% each. Choosing a donor kidney from a relative with a good tissue match can reduce the incidence of postoperative rejection. Secondly, the quality of the donor kidney directly affects the transplantation effect, which depends on the presence of shock, the length of thermal ischemia and total ischemia time, the integrity of the donor kidney and the perfusion situation before the kidney is cut. A thorough physical examination of the patient is performed before the operation to understand the anatomical variation of the artery, vein, pelvis and ureter of the donor kidney to ensure the integrity of the donor kidney. Simultaneous donor-recipient surgery can shorten the total ischemic time, and the thermal ischemic time is controlled to less than one minute. The lavage time and lavage volume can be accurately controlled. There is no shock condition and good blood supply before donor kidney excision. All these factors contribute to the good recovery of graft kidney function early after surgery. Again, the dosage of immunosuppressants is reduced because the immune status of the donor and recipient can be fully understood before surgery, suitable tissue mating can be selected, and preoperative immunological treatment of the donor and recipient can be performed in a timely manner, so the incidence of postoperative rejection is significantly reduced and the dosage of immunosuppressants is reduced, thus reducing the side effects of drugs on the body. Finally, another great advantage is that living relative kidney donor can schedule the operation according to the physical condition of the recipient, so that there is no need to wait for a long time and lose the time for transplantation, and there is sufficient time to complete the blood type test, PRA, HLA, CDC and other immunological tests before the operation, which can prevent the occurrence of hyperacute rejection. Sometimes, donor immunological treatment such as specific donor blood transfusion or specific bone marrow transfusion can be done before surgery to try to induce immune tolerance, thus reducing the incidence and degree of rejection after surgery.