Pertussis-like syndrome is a syndrome with clinical symptoms similar to whooping cough, which is commonly caused by adenovirus infections, but may also be due to Mycoplasma pneumoniae, respiratory syncytial virus, cytomegalovirus, and other infections. The pathogenesis of the disease is unclear. Symptoms include a paroxysmal, spasmodic cough that is more pronounced and may include cyanosis, shortness of breath, and dyspnea. At present, the clinic commonly used anti-infective, antispasmodic and asthma and sputum to the combination of treatment, some patients to apply glucocorticoids to treatment. It is recommended that patients with symptoms such as constant coughing should promptly go to the hospital to check the indicators of inflammation and the causative organisms, to clarify the specific causes, and then targeted treatment.