The term “blocking medication” should refer to HIV blocking medication, the side effects of which are not lifelong. The side effects of HIV blockers are temporary and reversible. Headache, dizziness, fatigue, gastrointestinal discomfort, insomnia and other symptoms may occur after taking HIV blocking medication, but these symptoms are temporary and there is no need to worry that the side effects of HIV blocking medication will last for life. If a patient suspects that he or she has experienced high-risk sexual behavior, taking the blocking medication in a timely manner under the guidance of a medical professional can reduce the risk of contracting HIV. Generally speaking, it is best to take the medication within 72 hours, the sooner the better. If you experience any of the above side effects after taking the blocking medication, you do not need to worry too much, it may just be a temporary side effect of the medication, but you should go to a regular hospital and be judged by a professional doctor for the specific diagnosis.