Oxymethadine, scientifically known as polyacrylamide hydrogel, is a colorless and transparent jelly-like liquid substance.In 2000, it was used on a large scale in the plastic surgery industry, from simple nose jobs and temple augmentation to larger breast augmentation, buttock augmentation, and filling of various soft-tissue depressions.On April 30th, 2006, the State Food and Drug Administration (SFDA) revoked Oxymethadine’s registration certificate as a medical device, and completely stopped its production and sale. Its production, sale and use were completely stopped. Because its monomer acrylamide is moderately toxic, poisoning the nervous system, damaging the kidneys, and causing damage to the circulatory system, the World Health Organization has classified the substance as a suspected carcinogen. Manifestations of adverse events of OMT include inflammation, infection, hard nodules, lumps, hardness, deformation, displacement, and residue. The surrounding tissues will be eroded after Omadin injection for rhinoplasty, and it has been clinically proven that it can cause the tissues to undergo changes such as vitrification and calcification. Surgical methods are difficult to completely remove the omertine, there will be part of the residue, and it is generally not recommended to do rhinoplasty immediately after the removal, especially silicone or expanded nasal prosthesis. As the tissues are in a sensitive state, there may be a higher rate of prosthesis rejection, or persistent tissue swelling, it is recommended that the interval between rhinoplasty again be more than 3~6 months. In some cases where the nasal deformity is severe after removal of the OMT and normal work and life is impossible, autologous tissues such as rib cartilage can be chosen for rhinoplasty to minimize the occurrence of surgical complications. Regular hyaluronic acid is usually metabolized and absorbed in half a year to a year. If there is swelling and infection in the nose after hyaluronic acid injection rhinoplasty, it is a sign of failure of rhinoplasty and the injectable hyaluronic acid needs to be removed. However, it is difficult to take out the injectable rhinoplasty completely, and part of the residual prosthesis may penetrate into the fascial tissue of the dorsum of the nose, which may produce rejection reaction to the re-implanted prosthesis. Therefore, it is recommended that the interval between rhinoplasty again is more than 3~6 months. Autologous tissues such as rib cartilage can be chosen for immediate rhinoplasty to obtain a more desirable nasal shape.