After BCG vaccination of newborns, the following types of vaccination reactions may occur: redness, swelling, or even pus at the local site of vaccination. Since BCG vaccine is made of Mycobacterium tuberculosis, in this case, Mycobacterium tuberculosis will cause a local immune response, which will lead to redness, swelling, or even pus at the vaccination site. In the vast majority of cases, this is a normal vaccination reaction and requires no special treatment. If the symptoms of suppuration are particularly severe, topical application of isoniazid can be given to the newborn. There are also systemic reactions, such as fever, cough, and even corn-like lesions in the lungs after BCG vaccination. It is caused by the relatively low immunity of the newborn, and the immune function can be checked for the newborn. If the immune deficiency, it is prohibited to give the child other vaccinations.