The 5-year survival rate of primary 12-cm hepatocellular carcinoma after hepatectomy was 30% to 50%, and the median survival time of patients after tumor recurrence and metastasis in liver transplant recipients with hepatocellular carcinoma was 7 to 16 months. The 5-year survival rate after surgical resection of secondary hepatocellular carcinoma is 25%~46%. Hepatocellular carcinoma is a malignant tumor of liver caused by hepatitis virus, cirrhosis, aflatoxin, certain chemical carcinogens and water and soil, etc. It is divided into two kinds: primary and secondary hepatocellular carcinoma. 1. Primary liver cancer: Surgical treatment of primary liver cancer is the most important means for long-term survival of liver cancer patients, mainly including hepatectomy and liver transplantation. The 5-year survival rate after hepatectomy is 30%~50%, and the median survival time of liver cancer patients with liver transplantation after tumor recurrence and metastasis is 7~16 months. 2. Secondary hepatocellular carcinoma: without metastasis in other parts, surgical resection is preferred. The 5-year survival rate after surgical resection of secondary hepatocellular carcinoma is 25%~46%. It should be noted that 12cm liver cancer patients can reduce the adverse effects of the disease through “early detection, early diagnosis and early treatment”, and many of them may survive for a long time, so it is recommended that patients set up confidence in the treatment and consult the doctor under the guidance of the doctor.