The itchy granuloma may be caused by the granuloma itself, or it may be caused by allergy to medication. Appropriate treatment measures should be taken for different causes, including external medication and hot compresses. 1. caused by inflammation: granuloma is caused by bacterial infection, there will be an inflammatory reaction and itchy feeling, you should use ofloxacin eye drops, erythromycin ointment for external application, you can also use dexamethasone ointment application to stop itching. 2. Drug allergy: in addition should find out whether the wheal itch is caused by allergy to the used drugs, if so, should stop the drug in time, change other drugs to use. It is recommended that patients should first clarify the itch is caused by which reason, under the guidance of the doctor to use the above drugs, in the process of using drugs should be avoided into the eyes.