Itchy small blisters on the soles of the feet may be caused by tinea pedis, herpes sweat, eczema and other diseases. 1. Tinea pedis: the causative organisms of this disease are mainly Trichophyton rubrum and Trichophyton mustelii, which can be transmitted through direct or indirect contact, and is related to the hot and humid environment, impaired immune function and other factors, and some of the patients will have itchy skin on the feet, blisters and other symptoms. 2. Sweat herpes: the etiology of this disease is still unclear, may be related to foot allergies, dermatophyte infection, mental stress, ultraviolet radiation, smoking, humid climate and other factors, mainly manifested in the hands or feet blisters with intense itching. 3. Eczema: Clinical studies have shown that the occurrence of this disease may be related to heredity, chronic infectious lesions, contact with allergens, hormone level disorders and other reasons. The rash can occur in any part of the body surface, such as hands, feet, etc. It can be manifested as erythema, itching, edema and papules. It is recommended that patients with itchy blisters on the soles of their feet go to the hospital, complete the relevant examinations, and clarify the specific causes, do not self-medication.