Cervical spine misalignment can present with headache, neck pain and paralysis. 1. Head: symptoms of vertigo and headache can occur. Vertigo is often caused by misalignment of the cervical 4 vertebrae, whose misalignment leads to ischemia of the vertebrobasilar artery system. Vertigo often occurs with head and neck movement. The headache is confined to the temporal and occipital regions, and the location of the headache is related to the direction of the subluxation. 2. Neck pain: Neck pain is one of the main symptoms, and the pain can radiate to both upper limbs or both lower limbs, and head and neck activities are restricted. The upper limbs may also have weakened muscle strength and sensory loss. 3. Paralysis: If the condition is serious, it may lead to paralysis. It is recommended to consult a doctor in time and standardize the treatment under the doctor’s guidance to reduce the adverse effects of the disease.