Etiology and clinical manifestations of lung cancer

  Lung cancer, known as bronchial lung cancer, is the third most prevalent cancer and the first among males, accounting for the highest mortality rate of human tumors.
  I. Risk factors of lung cancer
  1.Smoking: the primary causative factor
  2.85% of male lung cancer is related to smoking
  3.The younger the age of starting smoking, the greater the risk of lung cancer
  3, >30 cigarettes/day, >40 years, and SCLC relationship is obvious
  4.Filtered cigarettes are associated with ↑ incidence of adenocarcinoma: deep smoke inhalation
  5.Tobacco in the environment: “second-hand smoke”, smoking increases by 10 times, heavy smoking increases by 10-25 times
  6.Occupational exposure: asbestos, chromium, nickel, copper, tin, arsenic, uranium, etc.; electric and microwave radiation
  7, air pollution: industrially developed, serious air pollution areas; urban residents; urban suburbs than distant suburbs
  8, lung lesions: scarring, pneumoconiosis, silicosis, asbestosis
  9, diet: poor eating habits
  Second, clinical manifestations
  Symptoms caused by the primary tumor
  1. There is no symptom in the early stage, but with the development of lesion, the following symptoms can be found.
  ①Cough (45%-75%): the most common
  ②Coughing sputum
  ③Hemoptysis (27%-57%): intermittent hemoptysis or blood in sputum
  ④ Chest tightness, shortness of breath or wheezing: caused by bronchial stenosis
  ⑤ Recurrent pneumonia in the same lobe of the lung
  2.Symptoms caused by tumor metastasis
  ①Chest pain (1/4-1/2)
  ② Difficulty in swallowing, choking and coughing
  ③Respiratory difficulty: intrathoracic metastasis, pleural fluid
  ④Heartness of voice (2%-18%)
  ⑤Diaphragmatic paralysis
  ⑥Superior vena cava obstruction syndrome
  ⑦Pericardial effusion, arrhythmia
  ⑧Supra-pulmonary sulcus syndrome
  3.Late stage symptoms
  ①Metastasis to lymph nodes: lymph node enlargement
  ②Metastasis to brain and CNS: headache, vomiting, and even coma
  ③Metastasis to bones
  ④Metastasis to liver
  4.Other systemic manifestations
  ①Weight loss
  ②Lack of energy
  ③Anorexia
  ④ Cachexia
  ⑤ Fever
  Early screening is an important method to detect early lung cancer, and the following conditions should be alerted.
  1. Irritating dry cough that lasts for 2-3 weeks and the treatment is ineffective, or the nature of the original cough changes
  2. Repeated hemoptysis or chest pain
  3. Recurrent pneumonia in the same area
  4. Unilateral limited croup, limited emphysema, and pulmonary atelectasis
  5, unexplained arthralgia and pestle-like fingers (toes) of the extremities
  6, pulmonary tuberculosis after anti-tuberculosis treatment, no change or increase in shadow
  7, lung abscess of unknown cause, no toxic symptoms, no large amount of pus sputum
  8, hemorrhagic pleural fluid or pleural fluid growing rapidly during the treatment
  9, isolated round lesions and unilateral hilar shadow increase
  10.Age older than 45 years old, especially smokers, regardless of whether they have symptoms or not, it is better to have an annual physical examination, including chest X-ray and left chest CT examination if necessary.
  Treatment of lung cancer
  Methods: surgery, chemotherapy, radiotherapy, biological therapy, Chinese herbal medicine, supportive therapy, its
  Early detection and early treatment, stage I lung cancer may be cured by surgery, with a 5-year survival rate of 70-80%, stage IV-V 5-year survival rate <20%, and most of them die within 2 years
  Prevention: develop good living habits, quit smoking, stay away from pollution, maintain a happy mood, and have regular medical checkups.