Taking amoxicillin for headaches usually doesn’t work, there are multiple causes of headaches, the common types of headaches are migraine, tension headaches, cervicogenic headaches, cluster headaches, and none of the above common types of headaches have anything to do with infections in the body. In the case of tension headaches, you often need to take Myrna. Migraines require ibuprofen, and cervicogenic headaches require medications such as pregabalin and gabapentin. There are also other types of headaches, such as hypertensive headaches, which require antihypertensive medication, and cluster headaches, which require hormones or oxygen. There are also headaches caused by intracranial infections, such as those caused by bacterial meningitis, for which taking amoxicillin usually doesn’t work, and intravenous cephalosporin antibiotics usually do.