Prevention and treatment of obesity

  With the rapid development of China’s economy, the improvement of national living standards and lifestyle changes, obesity is no longer the preserve of Western countries. Obesity is happening to our nationals. The medical definition of obesity refers to excessive accumulation of body fat and (or) abnormal distribution. Weight gain is a multi-factorial chronic metabolic disease, general weight more than 10% of the standard weight for overweight, weight more than 20% of the standard weight that is obese. Genetic factors, high-calorie, high-fat diet, and reduced physical activity are the main causes of obesity. Statistics predict that in the next 10 years, China’s obese population will exceed 200 million, so obesity has become a serious public health problem facing China.  Obesity can be divided into physiological obesity and pathological obesity. The former refers to the normal physiological situation, due to the body’s own needs, so that the fat accumulation of excessive state, such as pregnancy and lactation obesity, and some special occupations such as weight lifters, sumo wrestlers. Simple obesity belongs to the physiological obesity, accounting for 95% of obese people, the formation of the main reasons are: 1, genetic factors: mainly the parents of physical heredity to their children, most experts believe that multi-factor heredity.  2, social environment factors: many people’s social concept of difference, as well as can not resist the temptation of food.  3, psychological factors: in order to relieve mood worries, eat to vent and cause overeating.  4, and exercise related factors: the energy intake can not be consumed through exercise, making fat accumulation and lead to the occurrence of obesity. Pathological obesity is common in hypothalamus, pituitary gland disease, hypothyroidism, Cushing’s syndrome, etc.. Such obesity with the treatment of the original disease, the body shape can gradually restore.  Obesity can lead to cardiovascular and gallbladder diseases as well as hypertension, hyperlipidemia, type 2 diabetes, stroke, cancer and other diseases. Therefore, reducing the occurrence of obesity can prevent and delay the emergence of diseases. At present, the prevention and treatment of obesity mainly from the following three aspects: 1, diet therapy: control excessive food intake, reduce excessive energy intake, balanced diet structure, control the intake of animal fat, change the habit of eating snacks and sweets, quit smoking and alcohol, low salt diet.  2.Exercise therapy: increase the amount of exercise appropriately to increase the chance of calorie consumption.  3, drug therapy: non-preferred method, can be divided into three categories ① appetite suppressants, such as sibutramine, can act on the central nervous system to suppress appetite, increase the feeling of satiety, so as to reduce food intake, weight loss, but the side effects are nausea, dry mouth, loss of appetite, tension, constipation and insomnia.  ②Metabolic enhancers: such as thyroxine tablets, which can increase energy expenditure by promoting metabolism to reduce body weight.  ③ lipase inhibitors: such as orlistat, can inhibit the absorption of fat and reduce energy intake to achieve the purpose of weight loss.  4.Psychological treatment: maintain a good and healthy mood, abandon the social concept of “to eat is bliss”, avoid overeating, especially to avoid venting worries and emotional instability through diet.  5.Surgical treatment: only limited to serious obesity, through the above treatment effect is not good obesity patients: such as fat aspiration, gastric narrowing surgery, jejuno-ileal bypass surgery, small intestine bypass surgery, etc.. For pathological obesity, treatment can be carried out for the cause, and can be combined with the above multiple ways for comprehensive treatment.