Cranial repair surgery is a routine surgery in neurosurgery, and it is also a surgery with a very long history, as our ancestors clearly performed such surgical practice thousands of years ago, which shows the importance of cranial repair surgery. In the current social environment, various risk factors are complicated and diverse, such as traffic accidents, production safety accidents, falling objects, etc., accidents are frequent, and some craniotomy has to be performed due to some craniosynostosis, which may eventually cause cranial defects, so cranial defects are now a common disorder in neurosurgery. For cranial defects, a very direct and effective way to deal with this disorder is to perform cranial repair surgery in time. Some patients ask if repair surgery is necessary. Cranial defects can cause great harm and impact on the human body, producing a series of cranial defect syndrome, threatening the health of the body, and may even directly endanger life. Therefore, timely cranial repair surgery is very necessary. The neurosurgical guidelines require that cranial repair should be performed in a timely manner if the cranial defect area is more than three centimeters in diameter, or if there are corresponding symptoms, or if it has a great impact on the aesthetic appearance. At present, the skull repair surgery technology has been relatively mature, and the factor that has a great influence on the repair effect is the choice of skull repair materials. Currently, titanium mesh is the most widely used material for skull repair, but there are some defects and shortcomings in the process of using this metal material, which is not very ideal. At present, a new polyetheretherketone peek material with more advanced and better performance has emerged, which has excellent performance and is very close to human autologous cranial bone, and has achieved ideal results and good feedback in application. Our team is widely using this advanced polyetheretherketone peek material for cranial repair surgery, and the team is constantly improving and upgrading the technology and optimizing the design of the material, adding the concept of cosmetic plastic surgery, thus the peek cranial repair and plastic surgery carried out comprehensively can obtain the overall unity of anatomical integrity, functional perfection and aesthetic appearance, and the effect is very ideal, which is well received by the majority of patients with cranial defects The results are very satisfactory and well received by patients with cranial defects and their families.