Feeling pain even after 26 days of cholecystectomy may be due to wound infection, bile reflux, and pleurisy. 1. Wound infection: After a patient undergoes cholecystectomy, it may lead to wound infection. Wound infection can cause poor healing and inflammation of the surrounding tissues, which can lead to pain. 2. Bile reflux: after cholecystectomy, some patients may experience bile reflux. When bile reflux occurs, the refluxed bile will enter the upper gastrointestinal tract, which will cause patients to have pain and burning sensation. 3. Pleurisy: After cholecystectomy, it may lead to pleurisy, and patients will have fever, chest tightness, chest pain and other symptoms, and the pain will be aggravated when pressing. It is recommended that patients should seek medical treatment in time if they have any physical discomfort after the operation.