46 years old menstruation for 3 months without menstruation, if it is caused by the normal menopause of women, it is considered normal, without special treatment; if it is caused by endocrine disorders, endometrial disease, etc., it is necessary to use estrogen and progesterone drugs or surgical treatment. It is recommended to consult a doctor in time to clarify the condition and not to use drugs blindly. 1. Normal menopause: If the ultrasound examination indicates that the endometrium is not more than 4mm, no dominant follicles are seen in the ovaries and the sex hormone examination suggests that the level of estrogen is low and the level of gonadotropin is obviously elevated, and disease factors are ruled out, then women who do not have menstruation should consider that it is related to the decline of ovarian function, and the specifics should be judged by the professional doctor, and then menopause should be regarded as normal menopause, and there is no need for any special treatment. 2. Disease: If the endometrium is found to be thicker, it is considered that the patient can’t strip the endometrium due to the lack of progesterone in the body because of the lack of ovulation, so there is no menstruation, and it may be endometrial polyps, hyperplasia, or even malignant changes, etc. It is necessary to follow the doctor’s instructions to adjust the menstruation through the ethinyl estradiol cyclopropylpropanedione tablets, dieldroxyprogesterone and other estrogenic hormone drugs, or to carry out a biopsy of the endometrium, so as to avoid or exclude the endometrial disease. In addition, if a woman has excessive sweating, insomnia, vaginal dryness and other menopausal symptoms after stopping menstruation, after ruling out drug contraindications can be supplemented with low-dose estrogen, such as estradiol valerate, under the guidance of a doctor to alleviate the symptoms, do not use their own medication to avoid venous thrombosis and so on. For 46-year-old women who have not had a period for three months, it is recommended that they go to the gynecology department of a regular hospital to improve ultrasound, sex hormones and other related examinations, and to clarify the cause of the disease under the guidance of the doctor’s active treatment.