Nodules caused by epididymitis are called inflammatory nodules, which can be treated by medication, surgery and general treatment. 1. Drug treatment: For nodules caused by epididymitis, antibiotic drugs can be applied under doctor’s guidance first, such as ceftazidime, levofloxacin, ofloxacin, etc. After the inflammation is controlled, the nodules can be eliminated by themselves. After the inflammation is controlled, the nodules can be eliminated by themselves. 2. Surgery: If the nodules can not be eliminated after inflammation control, surgery can also be taken to remove the nodules. 3. General treatment: patients should rest more during the treatment, can be braked or bed rest, ensure reasonable nutrition. During the period can also use 50% magnesium sulfate solution wet compress, can reduce local redness and swelling, promote inflammation subside. For patients suffering from epididymitis nodule, should go to the regular hospital, according to the individual situation, choose the appropriate way of treatment.