Amoxicillin generally does not cause symptoms of blood in the urine, hematuria may be the cause of urinary tract infections, urinary tract stones and tumors of the urinary system, can be given levofloxacin, lithotripsy granules, extracorporeal lithotripsy, surgical resection of tumors, respectively, for treatment. Amoxicillin is a broad-spectrum β-lactam antibiotic commonly used in the clinic, which has antibacterial effect on respiratory tract infections and genitourinary tract infections caused by bacteria, and does not have nephrotoxicity, which usually does not lead to hematuria. 1. Urinary tract infections: such as pyelonephritis, cystitis, urethritis, etc., the mucous membrane can be seen as congestion and edema during infection, accompanied by scattered small hemorrhagic spots, which can be manifested as fever, hematuria, lumbar and dorsal pain, bladder irritation, and can be given antibiotics such as levofloxacin for treatment. 2. Urinary tract stones: hematuria is related to the damage of stones to the mucous membrane of the urinary tract, usually manifested as microscopic hematuria after activity, and a few can be seen as microscopic hematuria, according to the size and location of stones, the treatment plan is different, and can be given to lithotripsy particles, extracorporeal shock wave lithotripsy or surgical removal of stones and other methods of treatment. 3. Urological tumors: such as kidney cancer, bladder cancer, prostate cancer, etc. Tumor invasion will lead to normal tissue hemorrhage and necrosis, which will be manifested as intermittent painless hematuria, and often need to be removed by surgery after clear diagnosis. There may be other reasons for hematuria, so it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or standardized treatment.