Prostate 59mmx39mmx38mm is considered a more serious situation. Prostate 59mmx39mmx38mm belongs to the prostate hyperplasia, and at present the hyperplasia is more obvious, easy to lead to urinary urgency, frequent urination, urinary incontinence, nocturia, urination difficulties and other symptoms, need to cooperate with the doctor in time to take treatment. For patients with prostate hyperplasia, medication can be taken first, commonly used drugs are α-blockers, such as terazosin, dorazosin, to help alleviate the symptoms of bladder outlet obstruction; M-receptor antagonists, such as tolterodine, can help to improve the prostate enlargement caused by urinary urgency, frequent urination and other symptoms; 5α reductase inhibitors, such as finasteride, can inhibit the conversion of testosterone to dihydrotestosterone. If prostate hyperplasia is more serious and the effect of conservative treatment is unsatisfactory, surgical treatment can be adopted, such as transurethral prostate electrocision, transurethral prostatectomy, open prostatectomy, and so on. Patients with prostate volume of 59mm39mmx38mm should actively cooperate with doctors to take treatment to avoid aggravation of the condition.