Osteofibrosis is a disease in which the bony structure is replaced by some fibrous structure. This lesion causes the gradual resorption of normal bone and bone tissue, which then gradually evolves into spindle-shaped bone fibers that can cause the loss of the physiological function of the bone. Although the disease is not self-curing, it must be treated early and actively, and most of it can be improved or even cured with proper treatment. Treatment is mainly based on surgery, which can be used to remove the local bone fiber lesion and then to treat it with bone grafting, or to consider direct surgical radical treatment. In general, attention should also be paid to avoid overexertion in life.