The b-type natriuretic peptide precursor is considered to be the N-terminal I B-type natriuretic peptide precursor, an indicator for the diagnosis of heart failure. N-terminal a B-type natriuretic peptide precursor is an important indicator for evaluating heart failure. Heart failure is a pathological state in which the heart’s function changes abnormally and cannot meet the metabolic needs of the body’s tissues and cells. Symptoms such as weakness, chest tightness, shortness of breath, and drooping edema may occur. It is generally a serious stage in the development of diseases such as hypertension, diabetes mellitus, and rheumatic heart disease, and may even be life-threatening. The normal value for adults under 50 years of age should be less than 450 pg/ml; the normal value for those over 50 years of age should be less than 900 pg/ml. If the result is within the reference range, it is considered that heart failure is not present; if it exceeds it, it suggests the presence of heart failure. When heart failure occurs, in addition to checking the N-terminal a B-type natriuretic peptide precursor, further examination of electrocardiogram, cardiac ultrasound, cardiac enzymes and other items disease treatment.