Generally it is more painful to have a colonoscopy, the pain of anesthesia is the same as the pain of an injection and infusion, while the pain of having a colonoscopy may last for the whole process of having a colonoscopy. Medications should be applied under a doctor’s supervision. Doing colonoscopy is an invasive examination, first you need to inflate the intestines, and then the colonoscope needs to be turned in the intestines along the physiological curvature of the intestines, in order to fully observe the condition of the intestinal mucosa, so in the process of inflation and turning the intestines may irritate the intestinal tract, abdominal pain, abdominal distension, the pain of doing a colonoscopy may last for the whole process of doing a colonoscopy. The pain of anesthesia is the same as the pain of injection and infusion. Since the colonoscopy is done by giving anesthetics through intravenous infusion, there will be pain only when the injection is started and there will be no discomfort during the anesthesia. Patients may experience mild dizziness and nausea upon awakening, but these symptoms will return quickly due to the relatively short half-life of propofol. Before the colonoscopy, it may be necessary to take bowel cleansing laxatives to prepare the intestinal tract, and also need to complete the electrocardiogram and other related tests, if you need to do a colonoscopy, please follow the doctor’s instructions for the relevant preparations.