If the patient’s liver function is checked by blood sampling, which indicates that the patient’s glutamic aminotransferase and glutamic oxalacetic aminotransferase are above 100 U/L, the patient is mostly considered to have liver insufficiency and liver cell necrosis. The most common cause is that the patient may have viral hepatitis, or autoimmune hepatitis, as well as the patient’s long-term alcohol consumption, long-term drug use, can cause the patient’s transaminases to rise, respectively, called viral hepatitis, autoimmune hepatitis, as well as alcoholic hepatitis, drug hepatitis may. In this case, the patient needs to have a blood test for hepatitis B tri-system and hepatitis C antibodies to see if the patient has the possibility of chronic viral hepatitis. In addition, if necessary, the patient will need to have blood drawn for autoimmune correlation tests, especially antinuclear antibodies. If the anti-nuclear antibodies are positive, the patient will need an ultrasound-guided liver aspiration biopsy if necessary. After pathologic diagnosis, the cause of hepatocyte necrosis can mostly be confirmed as a viral infection or autoimmune hepatitis. In patients who have been drinking alcohol for a long time or taking medications for a long time, it may further cause the patient to have elevated transaminases and bilirubin. In this case, the patient needs to be actively treated with hepatoprotective therapy, and intravenous infusion of hepatoprotective drugs is recommended for hepatoprotective therapy.