The penile folliculitis is an inflammation of the hair follicle that usually occurs at the root of the penis, mostly caused by Staphylococcus aureus infection, mainly manifested as a rash, pustules around the hair follicle, and may be accompanied by redness, itching, pain and other symptoms. The patient needs to go to the hospital in time, if there is a pustule, first need to use saline or hydrogen peroxide timely debridement, and actively carry out the corresponding treatment. 1, drug treatment: can be under the guidance of a professional doctor topical iodophor lotion, potassium permanganate solution, chlorhexidine gluconate and other antibacterial lotions to clean the penis, and use compound polymyxin B ointment, erythromycin ointment and other antibiotic ointment for treatment. It can also be treated with a combination of oral antibiotic medications such as doxycycline and cefuroxime, and antibacterial medications such as clindamycin, azithromycin and amoxicillin. Some Chinese herbs can also be used to help relieve the symptoms, such as wild chrysanthemum, serpentine, and dioscorea. 2. Physical therapy: In addition to medication, patients can also undergo supplemental treatment with red light or helium-neon laser irradiation to help recover from symptoms. If the symptoms are still not improved after taking the above-mentioned ways, or there is a situation of continuous aggravation and recurrence, the hair follicles can be destroyed by means of laser hair removal to achieve the purpose of eradication, and laser hair removal has the advantages of less complications and quicker results; 3, surgical treatment: if the patient’s symptoms are heavy, such as the appearance of a large volume of carbuncle, surgical treatment can be carried out after local anesthesia to cut open the lesion and draw out the pus, and appropriate The patient should be treated with antibiotics to avoid infection. In addition, these patients should avoid sexual intercourse during treatment and follow the doctor’s instructions to administer the medication in the right amount and on time. And after treatment, daily attention should be paid to keep the penis area dry and clean, avoid wearing too tight or poorly ventilated underwear, so as not to cause some wear and tear on the penis, to help reduce the chances of recurrence.