1.Is there no treatment for advanced kidney cancer? Clinically, advanced kidney cancer refers to “metastatic kidney cancer”. For this kind of patients, a comprehensive treatment based on internal medicine can be used. In recent years, domestic and international studies have recommended the use of molecular targeted drugs for the treatment of metastatic kidney cancer. Several randomized and controlled clinical studies have found that targeted drugs can significantly extend the progression-free survival time of metastatic kidney cancer patients, control local tumor growth, and play a role in treating or controlling tumor progression. Currently, the officially approved molecular targeted drugs listed in China are Sotan and Doxorubicin. In addition to these, cytokine therapy, such as interferon and interleukin-2, can also be used. For patients with bone metastasis, local tumor recurrence, regional and distant lymph node metastasis, palliative radiotherapy can achieve the purpose of relieving pain and improving survival quality. 2.What are the non-surgical treatments for kidney cancer? Non-surgical treatment methods of kidney cancer include (1) Minimally invasive treatment. Radiofrequency ablation, cryoablation and high-energy ultrasound focusing are commonly used for the treatment of small kidney cancer patients who are not suitable for surgery; (2) renal artery embolization. It can be used as a palliative treatment option to relieve symptoms for patients who cannot tolerate surgery. (3) Internal drug therapy, commonly used are molecular targeted therapy and cytokine therapy. Do radiotherapy and chemotherapy have therapeutic value for kidney cancer? The therapeutic value of radiotherapy and chemotherapy for kidney cancer is limited. Chemotherapy is currently limited to the treatment of patients with metastatic non-clear cell carcinoma. Palliative radiotherapy can achieve the purpose and effect of relieving pain and improving survival quality for patients with bone metastasis, local tumor recurrence, regional and distant lymph node metastasis.