Severe constipation may be caused by dietary factors, slow intestinal peristalsis, intestinal flora imbalance, and anorectal diseases. Patients with severe constipation can take lactulose, and if necessary, go to the hospital to find out whether it is related to organic pathology. Lactulose is a synthetic disaccharide drug, the drug when taken can regulate the physiological rhythm of the colon and help relieve the symptoms of constipation. Lactulose can stimulate gastrointestinal peristalsis when taken to keep the bowels open and relieve constipation. If indigestion, intestinal mucosa secretion of mucus is reduced, resulting in slow intestinal peristalsis fecal retention, you can take lactulose to help relieve the symptoms of constipation. Lactulose can also be given to help relieve constipation if you often eat hard-to-digest, high-protein meats, have less physical activity, or consume too little fresh fruits and vegetables, resulting in slow bowel movements. Constipation caused by intestinal flora imbalance, can be given at the same time probiotic drugs, such as bifidobacteria to regulate. In addition, some studies have confirmed that lactulose has a small effect on blood sugar, but for people with diabetes and poor blood sugar control still need to be cautious, and need to be used under the guidance of a doctor. If you can’t relieve your symptoms through the above methods, go to the gastroenterology department of the hospital if necessary to find out whether it is related to intestinal diseases, such as hemorrhoids, intestinal polyps, intestinal obstruction, benign and malignant tumors.