There is no so-called “fastest” solution for dry throat and dry mouth, and you need to choose the appropriate way according to your own condition, such as general treatment, medication and so on. 1. General treatment: if you have long-term open-mouth breathing, do not like drinking water, etc., you can improve the sleeping pattern, such as sleeping in the side position, drink more water, avoid eating spicy and stimulating foods, and strengthen outdoor activities. 2. Drug therapy: some patients have diabetes or autoimmune diseases, need to regularly apply hypoglycemic drugs and symptomatic treatment; some patients have chronic pharyngolaryngitis, can contain iodine-containing laryngeal tablets, and physiological saline or chlorhexidine solution can be used to gargle diligently on weekdays. If the combination of pain and discomfort, can be local nebulizer treatment, such as physiological saline, budesonide suspension. Therefore, the appearance of oropharyngeal discomfort is recommended to consult a regular hospital in a timely manner, a clear diagnosis and treatment.