Sleeping at night chest pain up for a while on the pain, there are a variety of reasons can lead to, generally considered improper sleeping posture, reflux esophagitis, coronary heart disease and other diseases. 1. Improper sleeping position: If you sleep in a prone position or supine position at night, it can compress the local muscles and lead to poor blood circulation, which can be relieved through appropriate activities when you get up. 2. Reflux esophagitis: As the pressure in the esophagus decreases during sleep, stomach acid refluxes into the esophagus, resulting in retrosternal pain, and the pain can be relieved or disappear after getting up with the pressure at the end of the esophagus increasing. 3. Coronary heart disease: coronary heart disease is caused by spasm and narrowing of coronary arteries, if the patient is in myocardial ischemia, etc., due to the condition is not too serious, there may be transient chest pain, and the symptom of chest pain can be relieved by oneself after getting up. In addition to the above diseases, there are many other causes can lead to, need to go to the hospital, a clear diagnosis of the cause of the targeted treatment, you can not randomly use drugs.