Callus, that is, callus, long callus on the hand can be removed through the blade, or the use of drugs and so on. Callus is due to long-term friction of the hand skin caused by the performance of limited keratosis plaques, yellow, hard surface, most patients do not have obvious symptoms, available hot water soak callus parts, to be softened by the medical professionals with a surgical blade to remove the surface of the stratum corneum. It is not recommended that patients attempt the treatment themselves to avoid infection. In addition, exfoliators such as salicylic acid ointment and retinoic acid ointment can be used to gradually soften the keratosis pilaris. All medications should be used under the guidance of a medical professional to avoid adverse reactions.