NSE indicator 19.81μg/L is generally problematic, a positive result, suggesting that the human body may be suffering from tumor disease. NSE is a neuron-specific enolase, which is involved in glycolysis in the human body, and mainly exists in the nervous tissue and neuroendocrine tissue, and its normal reference range is generally no more than 12.5μg/L (according to the reference indexes of the testing organization), and 19.81μg/L is an abnormal result, i.e., NSE is positive. NSE positivity can be seen in small cell lung cancer, neuroblastoma, pheochromocytoma, melanoma and other tumor diseases, and it is of great significance in the differential diagnosis between small cell lung cancer and non-small cell lung cancer. Positive NSE suggests that the human body may be suffering from the above mentioned tumor diseases, in this case, further relevant examinations should be completed, such as cranial chest CT, cranial nuclear magnetic scanning, etc., to clarify the reasons for the elevation of this index, and then follow the medical advice to deal with the cause.