Hepatitis B major triple-positive refers to positive hepatitis B surface antigen and hepatitis B core antibody, and positive e antigen; while hepatitis B minor triple-positive is positive for e antibody and negative for e antigen in addition to positive hepatitis B surface antigen and hepatitis B core antibody. Generally speaking, hepatitis B major tri-positive is highly infectious and has a high viral load; hepatitis B minor tri-positive has a low viral load, but it is not possible to determine the size of infectiousness by whether the five hepatitis B items are major or minor tri-positive, and liver function, hepatitis B virus quantification, liver, gallbladder and spleen ultrasound, etc. should be checked to make a comprehensive assessment. Once a positive hepatitis B surface antigen is found, whether it is a major or minor triplet, it is necessary to come to a professional hospital for examination, and only the quantitative level of hepatitis B virus DNA can tell whether hepatitis B is highly or less contagious.