Major triple yang refers to the formation of hepatitis B major triple yang in normal people who are not vaccinated against hepatitis B and do not have antibodies to hepatitis B in their bodies after being infected with the hepatitis B virus. The hepatitis B virus is mainly transmitted through blood, sexual contact and mother-to-child transmission. For people who are not vaccinated against hepatitis B and do not have antibodies in their bodies, they can be infected with the hepatitis B virus through the above ways, and because the immune regulation of the body does not clear the hepatitis B virus, the hepatitis B virus replicates and multiplies in the body, and the five hepatitis B tests are one, three and five positive, suggesting that the patient is a major triple-positive hepatitis B. Therefore, patients with hepatitis B major tri-positive are infected with hepatitis B virus and finally become hepatitis B infected.