Acute hepatitis B patients can be cured in a few months after proper treatment and reasonable recuperation, at this time, the liver function is normalized and the antigen index of hepatitis B virus has turned negative. Patients can get pregnant after a period of recuperation and full recovery of physical strength. Patients with chronic hepatitis B should first find out the severity of their condition before deciding whether to get pregnant. If the patient belongs to virus carrier, long-term follow-up examination of liver function series is always normal, HBVDNA quantitative negative, ultrasound does not indicate cirrhosis, can consider pregnancy. If the patient’s hepatitis B inflammation is in the active stage, check liver function abnormalities, self-conscious fatigue, loss of appetite, abdominal distension, etc., this should be avoided to get pregnant, the active stage of liver inflammation hard pregnancy, the body burden increases, the liver has to complete more work, hepatitis is not easy to recover, but prone to lead to severe hepatitis, endangering the life of pregnant women. In addition, it is not favorable for the development and growth of the fetus. Therefore, patients with active hepatitis B should first receive regular treatment, including antiviral and immunomodulatory therapy. When the liver function is normalized and the viral replication index becomes negative or the replication ability is reduced, then pregnancy can be carried out, which is beneficial to both mother and child. If ultrasound examination reveals that the hepatitis has progressed to the level of cirrhosis, it is best not to get pregnant. For patients with active hepatitis, after treatment, the condition is stabilized and the liver function is normal for more than half a year, it is safer to get pregnant. Hepatitis B patients once pregnant, should terminate the use of a variety of drugs with hepatotoxicity, such as antibiotics, anti-tuberculosis drugs, treatment of diabetes drugs and so on. Hepatitis B pregnant women, especially hepatitis B “triple positive” pregnant women, should be in the seventh, eighth and ninth months of pregnancy, respectively, injected with a high-efficiency hepatitis B immunoglobulin, in order to prevent intrauterine infection of hepatitis B virus, so that newborns are born healthy.