Ground-glass nodular shadow in the lower lobe of the right lung is not suggestive of allergy, and there is generally no association between the two. People with allergies are prone to allergic reactions after contact with allergens, such as pollen, animal fur, certain foods or medications, etc. The main manifestations are itchy skin and rashes, as well as sneezing, coughing, runny nose, watery eyes and other symptoms, and in severe cases, respiratory distress, angioedema, anaphylaxis, and so on. Allergic pneumonia is a pulmonary inflammatory reaction disease induced by repeated inhalation of organic dust antigens in susceptible individuals. Clinically, it is mainly manifested as repeated acute episodes or persistent progressive development of dyspnea, and imaging is mainly characterized by the characteristic manifestations such as nodules with fine bronchiolar centers, interspersed or accompanied by solid changes in the patchy ground-glass shadows, and mosaic signs formed by gas trapping and closure. Ground glass nodular shadow in the lower lobe of the right lung may be caused by lung infection, tuberculosis, pulmonary nodular disease, malignant tumors and other diseases, which are generally less related to allergic factors. The nature of the nodules can be clarified through further improvement of relevant examinations and timely treatment. If ground-glass nodular shadows are found in the lower lobe of the right lung, it is recommended that the patient should consult the doctor in time, improve the examination, clarify the cause of the disease, and follow the doctor’s instructions for treatment.