A biopsy of the side of the lesser curvature of the gastric sinus is not necessarily problematic, and whether or not it is problematic should be judged based on the results of the examination, and cannot be generalized. A biopsy of the side of the lesser curvature of the gastric antrum is a biopsy of the suspected area at the lesser curvature of the gastric antrum taken during a gastroscopy to make a pathologic section for pathologic examination. Usually, the cellular pattern is observed under a microscope to determine the exact type and severity of the disease. The biopsy of the side of the lesser curvature of the gastric sinus is not necessarily a problem, it may be that the doctor found during the examination of the side of the lesser curvature of the gastric sinus there is congestion, edema, ulceration, atrophy or polyps and other lesions, and can not be sure of the specifics of their lesions, it will be biopsied for further examination, the specific question of whether or not there is a problem should be based on the results of the examination to determine. If the examination is gastritis, gastric erosion, gastric ulcer and other diseases, generally after active treatment can be effectively controlled, then there is generally no problem. However, if the examination reveals malignant lesions, such as gastric sinus cancer, the problem will be more serious. There is no need to worry too much about biopsy of the lesser curvature of the gastric sinus, which is a basic operation during gastroscopy. Patients should seek prompt medical attention, and the doctor will make a comprehensive evaluation based on all the test results.