Early intervention for at-risk children is very important. Early intervention refers to the enrichment of the external environment with educational activities for infants whose development deviates from normal, through which the intelligence of at-risk children improves or catches up with normal children. The younger the infant, the faster the brain develops, the more plastic the brain is, and the better the ability to compensate for damage, especially within the first year of life and especially in the first few months. Therefore, during the time when infants’ neurosynapses are rapidly increasing, the instability of neural circuits is exploited to give benign environmental stimuli to shape the optimal cortical cell structure. Clinical studies have proved that through early enrichment of all-round intervention and functional training, at-risk infants can obtain functional brain reorganization, maximize normal development of the affected children, prevent the development of abnormal postural reflexes or abnormal muscle tone, achieve the purpose of preventing neurological sequelae and improving population quality.