Most of the 0.4 cm bulges in the esophageal mucosa are not serious, but the details need to be analyzed and judged according to the condition. 1. Benign lesions: polyps and small adenomas originating from the submucosa of the esophagus or esophageal smooth muscle tumors are generally benign lesions. If the clinical symptoms are obvious, esophageal surgery can be performed to remove the tumor, which generally will not affect the survival of the patient. 2. Malignant lesions: This is usually an abnormal elevation under the esophageal mucosa, and the surface is not smooth and irregular, and the morphology is incomplete, which needs to be considered as a malignant lesion and needs to be diagnosed by pathology. If the disease is in the early stage, it can be treated by surgical resection; if it is in the late stage, it is often more serious and needs to be treated by chemotherapy combined with immunotherapy. It is recommended that the patient should go to a regular hospital to receive examination, and after a clear diagnosis, the specialist will decide whether treatment is needed.