Age spots, i.e. seborrheic keratosis, are mainly related to sunlight damage, natural aging, genetic factors, etc. The disease can be prevented by strengthening sun protection and reducing skin friction, etc. For age spots caused by different etiologies, they can be treated by general treatment, medication and physical therapy. 1. Prevention: In daily life, sun protection should be strengthened to reduce exposure to the sun; sunscreen should be applied or sunscreen hats should be worn when going out in hot weather; friction and scratching of the skin should also be reduced. 2. Treatment: (1) Drug therapy: for patients with small skin lesions, they can use topical Vitamin A acid cream, fluorouracil ointment, imiquimod ointment and other drugs. (2) Physical therapy: if the effect of external medication is not good, physical methods such as freezing and laser can be used. When age spots appear, it is recommended to consult a doctor in time and follow the doctor’s instructions to standardize the treatment, do not self-medication.