It is well known that smoking can cause a variety of respiratory diseases, such as chronic bronchitis, lung infections, and lung cancer. However, many people may not realize that smoking has a much more harmful effect on the cardiovascular system and that this harm far exceeds its adverse effects on the respiratory system.” The latest statistics show that 1 million people die each year from tobacco-related diseases in China, with 10-15% of them dying from smoking-related cardiovascular disease. In general, smoking can harm the health of the cardiovascular system through several mechanisms. First, smoking is a major killer of atherosclerotic cardiovascular disease. There are ten major risk factors for atherosclerotic cardiovascular disease, namely age, gender, genetic history, hypertension, hyperlipidemia, smoking, diabetes, lack of exercise, obesity, and stress. Among them, smoking is one of the most important risk factors that can significantly increase the risk of atherosclerotic disease. Smoke contains a variety of harmful components, of which carbon monoxide and nicotine are the main substances that cause damage to the cardiovascular system. Carbon monoxide can directly damage the vascular endothelial system, impairing the integrity of the endothelium, increasing the permeability of the vessel wall, and therefore increasing the risk of atherosclerotic lesions. At the same time, carbon monoxide can competitively bind to hemoglobin, significantly reducing its oxygen-carrying capacity and causing or exacerbating tissue and organ hypoxia. Nicotine can also harm the cardiovascular system through a variety of mechanisms, such as increasing sympathetic excitability, raising blood pressure, damaging the endothelial system, promoting platelet aggregation and thrombosis, and raising LDL cholesterol levels. Whether it is carbon monoxide or nicotine, their ultimate effect on the cardiovascular system is to induce or aggravate atherosclerotic lesions and cause damage to target organs such as the heart, brain, kidney or peripheral vasculature. Epidemiological and clinical studies have shown that the incidence of coronary heart disease is significantly higher in smokers than in nonsmokers. Foreign studies have found that the risk of non-fatal myocardial infarction in smokers is three times higher than in nonsmokers, and is a risk factor second only to diabetes. Epidemiological survey data show that the incidence of coronary heart disease is 3.5 times higher in smokers than in nonsmokers, and the death rate of coronary heart disease is 6 times higher, and the incidence of myocardial infarction is 2 to 6 times higher. A domestic survey found that the attributable risk ratios for smoking in coronary events were 15.2% and 16.1% for urban and rural residents over 20 years of age, respectively, and 10.3% and 10.4% for stroke, respectively. This shows that smoking is a significant risk to the cardiovascular system and has become one of the main risk factors affecting cardiovascular health and inducing cardiovascular events in our population. Second, patients with atherosclerotic disease are a high prevalence of smoking. Since the risk of atherosclerotic cardiovascular and peripheral vascular disease is significantly higher in smokers than in nonsmokers, and only a few of these patients have successfully quit smoking after a clear diagnosis of cardiovascular disease or even myocardial infarction, the proportion of smokers in this population is still significantly higher than in the general population. It is important to note that for those who have already experienced severe organ damage such as coronary artery disease, the adverse prognostic impact of smoking is even greater, and continued smoking can significantly increase the risk of developing major adverse cardiovascular events. More importantly, multiple risk factors, such as hypertension, hyperglycemia, hyperlipidemia, and obesity, are often entwined, as is smoking. The coexistence of different risk factors can have an additive or even amplifying effect on the cardiovascular system. If smoking is accompanied by high blood pressure and high cholesterol, the incidence of coronary heart disease increases 9-12 times. In the presence of other risk factors, the cardiovascular system may be even more compromised by smoking. Therefore, to minimize the risk of cardiovascular events, an integrated control strategy of multiple risk factors, including smoking cessation, is necessary. The risks of smoking are not limited to the smoker, but can be similar or even greater for passive smokers in their immediate environment. The nicotine content of the smoke produced by smoking is 1-3 times higher than the smoke inhaled by the smoker, and the carbon monoxide content is 4-5 times higher. Survey data show that passive smokers are 25-50 percent more likely to develop coronary heart disease than the general population. Smoking cessation significantly reduces the incidence of adverse events in patients with cardiovascular disease. After successful cessation, smokers have a 50% reduction in the incidence of coronary events, which is significantly higher than the risk reduction obtained by effective control of blood pressure, glucose, and lipids.