The principles of emergency treatment of coma are as follows: 1. pay attention to respiration and heartbeat, if there is respiration and heartbeat arrest, cardiopulmonary resuscitation, epinephrine, tracheal intubation and other resuscitation measures should be given immediately; 2. correct shock, if hypotension is found, rapid rehydration should be given, apply for blood transfusion if necessary, apply anti-shock treatment with antihypertensive drugs, glucocorticoids and other drugs; 3. deal with the original disease, pay attention to There is no head trauma or cerebral hemorrhage caused by hypertension, check the head CT if necessary, if there is cerebral hemorrhage seriously leading to brain tissue compression, midline deviation, brain hernia formation, emergency surgery should be given immediately to deal with it, if hypoglycemia is found, high sugar injection should be given immediately. If it is a heart problem, common myocardial infarction, thrombolysis or interventional therapy should be given immediately; 4. It can be given to promote wakefulness, and the commonly used drugs are naloxone and wakefulness.