The main manifestations of esophageal epithelial hyperplasia include heartburn, pain, dysphagia, and retrosternal pain. Epithelial hyperplasia occurs in the esophagus due to prolonged stimulation of inflammation, resulting in proliferative changes in the squamous epithelial mucosa of the esophagus, which can be seen in reflux esophagitis, esophageal cancer and other diseases. 1. Heartburn: due to esophagitis can cause gastric acid reflux, repeated stimulation of the esophagus, and then heartburn symptoms. 2. Pain and dysphagia: prolonged stimulation of gastric acid can cause pain, and it can also lead to pathologic hyperplasia of squamous-columnar epithelium in the middle and upper esophagus, resulting in esophageal stenosis, and then dysphagia occurs. 3. Poststernal pain: the columnar epithelium of the esophagus will cause ulcers after corrosion by acidic digestive juices, resulting in symptoms similar to gastric ulcers, which will lead to poststernal pain. If the patient has esophageal epithelial hyperplasia, it is recommended to go to the regular hospital in time, after clarifying the cause of the disease, under the guidance of the doctor for targeted treatment.