Painful urethra and constant urge to urinate in women is most commonly associated with acute cystitis, which is a sign of bladder irritation caused by acute cystitis. In addition to frequent and painful urination, there will be urgency, a burning sensation in the urethra during urination, and painful discomfort in the perineum or bladder area. This is related to the sexual life of women, as their urethra is very close to the vagina and anus and may be contaminated by both without contamination, which can cause acute cystitis. This time you need to do a routine urine examination to see, if the number of white blood cells in the routine urine increases, consider acute cystitis, you can take oral levofloxacin for three days, at the same time to urinate more, drink more water, do not hold urine, eat less spicy and stimulating food. If the frequency of urination is more serious, you can apply hot compresses to the bladder area. Usually, when cleaning the perineum after a bowel movement, wipe from front to back.