The more you drink water, the drier your lips are due to a number of reasons, which may be caused by psychogenic thirst, dry syndrome, diabetes, uremia and so on. 1. Spiritual thirst: If you suffer from spiritual thirst, you may have dry mouth, even if you drink water, but there is no obvious abnormality in all the examination indexes. 2. Dry syndrome: dry syndrome is a salivary gland disease, due to the tear gland and salivary gland lesions will lead to a decrease in salivary secretion, the more you drink water, the dryer your lips may appear. 3. Diabetes: is due to their own blood sugar is obviously over the limit, easily lead to plasma osmotic pressure increases, urine volume increased significantly, and then the symptoms of thirst. If blood sugar is not effectively controlled, the body will show persistent dry mouth, even if you drink water can not be relieved. 4. Uremia: due to central lesions, affecting the antidiuretic hormone, a large number of urination phenomenon, the body water reduction, will cause the more you drink water, the more dry lips phenomenon. If the more you drink water, the more dry lips, it is recommended to consult a doctor in time to identify the cause, and give effective treatment.