Untreated wet gangrene can lead to ischemic necrosis of tissues and, in severe cases, life-threatening sepsis. Wet gangrene must be treated in a timely manner because it can lead to ischemic necrosis of the corresponding tissues and organs. Over time, it can lead to the arrival of bacteria throughout the body through the blood circulation and, in severe cases, to infectious shock, sepsis, and multi-organ failure. The disease progresses rapidly and can often be life-threatening within two weeks. For the early stage of wet gangrene, surgery is needed to remove the necrotic tissues; antibiotic treatment, such as ceftriaxone sodium and other third-generation cephalosporins, can be used to kill the pathogenic bacteria; at the same time, the blood supply of the corresponding tissues and organs should be restored as soon as possible; rehydration therapy, try to remove the inflammatory factors in the body, and so on. It is recommended that patients go to the hospital in a timely manner, under the guidance of a physician, so as not to delay the condition.