There are many differences between Niu Huang Xie Poisoning Tablets and Huanglian Shangqing Tablets, mainly due to the different drug ingredients, different effects and different contraindications for people. 1. Different drug ingredients: oxalis detoxification tablets mainly by artificial oxalis, gypsum, rhubarb, platycodon, ice, andrographis, licorice and so on composition. Huanglian clearing tablets mainly by gardenia, Huanglian, Angelica dahurica, chrysanthemum, mint, licorice, cypress and so on. 2. Efficacy is different: Niu huang detoxification tablets biased in clearing heat and detoxification (clearing body heat and poisonous evil), mainly used for fire and heat caused by sore throat, mouth and tongue sores, swollen and painful gums, and eye red swelling and pain. Huanglian Shangqing Tablet is for dispersing wind and clearing heat, and is mainly used for gum pain, dizziness, mouth and tongue sores, earache, tinnitus, constipation, and short urination caused by wind-heat attacking the lungs and stomachs (the heat of the lungs and stomachs is very heavy). 3. Different contraindications: In addition to pregnant women, the contraindications of Niu Huang Xie Du Wei Tablet are not recommended for nursing mothers, infants and young children. Huanglian Shangqing Tablets are contraindicated for pregnant women and people with spleen and stomach deficiency (spleen and stomach weakness and cold). Although they are both common Chinese medicines, they should be used under the guidance of a professional doctor.